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Barbiturates may be practice forming. Tolerance, psychological and Bodily dependence may take place with continued use. (See “Drug Abuse And Dependence” and “Pharmacokinetics” sections.) Sufferers who've psychological dependence on barbiturates might boost the dosage or minimize the dosage interval devoid of consulting a medical doctor and

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Corticosteroids: Barbiturates surface to boost the metabolism of exogenous corticosteroids likely through the induction of hepatic microsomal enzymes. Individuals stabilized on corticosteroid therapy might call for dosage adjustments if barbiturates are included to or withdrawn from their dosage program.All medicines might induce Unwanted effects.

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